#358 | Dr. Sarah J. Buckley on Oxytocin, Safety, and the Biology of Birth

March 11, 2026

When Trisha was pregnant with her second baby, she read Gentle Birth, Gentle Mothering — a book that completely reframed how she understood labor, and to this day remains her favorite book on pregnancy. Trisha's second birth unfolded in just three hours, a stark contrast to her first. That book was written by Dr. Sarah J. Buckley, and we've long dreamed of getting her on the show. That day has finally come!

Dr. Buckley is a New Zealand–trained family physician and leading researcher on the hormonal physiology of childbirth, and today she walks us through the science of oxytocin and why it matters so profoundly in labor. We explore how the maternal brain modulates pain, how safety and privacy influence hormone flow, and why certain features of modern maternity care can unintentionally trigger stress responses that disrupt physiological birth.

This episode is a deep dive into the biology of labor — and what women truly need for it to unfold as designed.

In this episode, we discuss:

  • The "Safety Triad": Why feeling private, safe, and unobserved is a biological requirement, not a luxury.
  • The Pitocin Paradox: The shocking truth about synthetic "oxytocin", its unknown half-life, and why it doesn't offer the same brain benefits as the real thing.
  • The Epidural Gap: How numbing the sensation of labor interrupts your natural hormonal feedback loop.
  • The Baby’s Experience: What the fetal catecholamine surge is and what it means for your newborn’s first moments after birth.

Sarah Buckley

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About Cynthia Overgard

Cynthia is a published writer, advocate, childbirth educator and postpartum support specialist in prenatal/postpartum healthcare and has served thousands of clients since 2007. 

About Trisha Ludwig

Trisha is a Yale-educated Certified Nurse Midwife and International Board Certified Lactation Counselor. She has worked in women's health for more than 15 years.

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